[OA-17] The expression of CD15 in placental vessels belonging haemoglobin Bart's hydrops foetalis
Haemoglobin Bart can lead to hydrops foetalis (HF). Its placental findings include abnormally increased intermediate villi with immature endothelium. CD15 assists in diagnosis of delayed villous maturation by identification of foetoplacental endothelial immaturity. Thus, investigation of CD15 expression has benefit for understand pathophysiology of Hb Bart's HF. This study aimed to evaluate CD15 immunoreactivity in placental endothelium of Hb Bart's HF in comparison to that in other causes of HF. CD15 was performed in 14 cases of Hb Bart and 9 cases of HF by other causes...
[OA-05] Pancreatic islets of Langerhans and insolin secreting cells in haemoglobin Bart's hydrops foetalis
A finding of islet cell hyperplasia has been reported in infants of diabetic mothers and hydrops foetalis (HF), but no any report in haemoglobin (Hb) Bart's HF. The aim of this study was to analyse the morphometry of beta cells in Hb Bart. Pancreas from 10 Hb Bart cases and 9 controls were retrieved. ...
[P-06] Excess subchorionic fibrinoid deposition as another variant of maternal floor infarct/massive perivillous fibrin deposit
Maternal floor infarction (MFI) and massive perivillous fibrin deposition (MPFD) are placental disorders of unknown aetiology, associated with adverse obstetric outcome. Its morphology is characterised by marked increase in perivillous fibrinoid deposition in the intervillous space. The distribution of such fibrinoid deposition in MFI and MPFD often overlaps, suggesting both conditions represented the final common pathway for a number of different insults....
[P-05] Fatal spontaneous intraluminal intestinal haematoma: a paediatric case report
Disseminated intravascular coagulation (DIC) is the excessive activation of the coagulation pathway with thrombus formation, progressing to a consumptive coagulopathy with an imbalance between the fibrinolytic and antifibrinolytic systems, resulting in uncontrolled haemorrhage. Sepsis is the most common condition associated with DIC, usually manifesting as diffuse bleeding, commonly involving the gastrointestinal tract. However, intraluminal intestinal haematoma leading to obstruction is rare, and such patients usually improve with management. We report what we believe is the first case of a fatal intraluminal intestinal hematoma in an infant with DIC....
[P-04] Stillbirth classification by the International Classification of Diseases for Perinatal Mortality (ICD-PM) using stepwise analysis: a study from a teaching hospital in Thailand
The International Classification of Diseases for Perinatal Mortality (ICD-PM) coding was introduced in 2016, as a global system for reporting causes of perinatal death. The aim of this study was to classify stillbirths by the ICD-PM, comparing input from clinical data, placental pathology and autopsy results....
